Metagenics Mag Glycinate
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Background
Magnesium is an essential mineral that plays a crucial role in many physiological functions within the human body and is involved in over 300 enzymatic reactions. Some of these functions include: energy metabolism, helping convert carbohydrates and fats and proteins into ATP (form of energy used by cells); protein synthesis; nervous system functions such as nerve impulse transmission and muscle contractions; cardiovascular health, involved in maintaining a healthy heart rhythm and lowering blood pressure by relaxing and dilating blood vessels. Lastly, magnesium is also involved in maintaining optimal bone health as it plays a vital role in absorption and metabolism of calcium, phosphorous, and vitamin D.
Since magnesium stays in the body for 12 to 24 hours and is easily excreted, it is important to ensure an adequate daily intake of magnesium to make sure all aforementioned functions are carried out efficiently. Additionally, other factors such as over-farming, increase in consumption of processed and refined foods and alcohol, chronic health conditions, stress, and aging further increase the risk of inadequate magnesium intake in individuals. Several studies have shown magnesium deficiency to be quite prevalent in North America with deficiency rates around 34% in Canada and 48% in US. The data also found a higher percentage of women and the elderly population to be magnesium deficient in comparison to other population groups.
What Mag Glycinate offers
Each tablet contains 100mg of pure elemental magnesium in a bis-glycinate blend (amino acid glycine bound to magnesium molecules). The bis-glycinate form ensures optimal absorption by avoiding competition with other minerals. Additionally, this form also minimizes the common side effects of magnesium which will be looked at in more detail in the next section.
Why Mag Glycinate
When it comes to magnesium supplementation, it is crucial to choose the right form of magnesium due to its different uses and side effects. For example, magnesium oxide is in a highly absorbed form but also tends to cause the most gastrointestinal discomfort and diarrhea which is why it is widely used as a laxative. This form needs to be combined with other ingredients such as glycine and magnesium bis-glycinate chelate to help minimize these unwanted side effects. The magnesium form with the some of the highest absorption and least occurrence of GI issues and diarrhea is the bis-glycinate form, otherwise commonly referred to as magnesium glycinate. To further reduce these reactions, this product also contains glycine which helps curb gastrointestinal side effects further and ensures patient satisfaction.
In short, this magnesium supplement in the form of magnesium bis-glycinate, aka glycinate, will have the least occurrence of side effects while boasting a very high rate of absorption due to its molecular structure.
Dosage and precautions for Mag Glycinate
Directions: Take one tablet three times daily or as directed by your healthcare practitioner.
Caution: As with any natural health product, you should consult a healthcare practitioner on the use of this product. If pregnant, nursing or taking antibiotics or cardiovascular medication, consult your healthcare practitioner before use. Keep out of reach of children.
Storage: Keep tightly closed in a cool, dry place.
Mag Glycinate ingredients
Ingredient | Amount Per Serving | % Daily Value |
---|---|---|
Magnesium | 100 mg | 24%* |
Other Ingredients: Microcrystalline cellulose, stearic acid (vegetable), croscarmellose sodium, and silica.
Serving Size: 1 Tablet
This product is vegetarian, non-GMO, and gluten-free.
Servings Per Container: 120. Other serving size might also be available.
*Percent Daily Values are based on a 2,000 calorie diet.
{**Daily Value not established.}
References about Mag Glycinate
de Baaij, J. H. F., Hoenderop, J. G. J., & Bindels, R. J. M. (2015). Magnesium in man: Implications for health and disease. Physiological Reviews, 95(1), 1-46.
Volpe, S. L. (2013). Magnesium in disease prevention and overall health. Advances in Nutrition, 4(3), 378S-383S.
Rosanoff, A., Weaver, C. M., & Rude, R. K. (2012). Suboptimal magnesium status in the United States: Are the health consequences underestimated? Nutrition Reviews, 70(3), 153-164.
Schwalfenberg, G. K., & Genuis, S. J. (2017). The importance of magnesium in clinical healthcare. Scientifica, 2017, 4179326.
Health Canada. (2012). Canadian Nutrient File (CNF). Retrieved from Canadian Nutrient File (CNF) - Search by food
Health Canada. (2019). Summary of Health Canada's Assessment of a Health Claim about Magnesium and the Reduction of Risk of Type 2 Diabetes. Retrieved from https://www.canada.ca/en/health-canada/services/food-nutrition/food-labelling/health-claims/assessments/magnesium-reduction-risk-type-2-diabetes-summary.html
National Institutes of Health Office of Dietary Supplements. (2021). Magnesium Fact Sheet for Health Professionals. Retrieved from Office of Dietary Supplements - Magnesium
Zhang, X., Li, Y., Del Gobbo, L. C., Rosanoff, A., & Wang, J. (2016). Associations of dietary magnesium intake with mortality from cardiovascular disease: The NIH-AARP diet and health study. Journal of American Heart Association, 5(1), e002707.
Kurth, T., Diener, H. C., & Goadsby, P. J. (2012). Migraine and risk of cardiovascular disease: Systematic review and meta-analysis. British Medical Journal, 345, e5027.