Metagenics Bone Builder
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Background
Osteoporosis and osteopenia (loss of bone mineral density) are prevalent medical conditions amongst older adults with some studiers estimating that around 30 to 50 percent of women and men have low bone density with women being affected at a much higher rate. Factors affecting bone density range from physical activity and lifestyle factors such as smoking and excessive alcohol consumption to decreased levels of estrogen in women and testosterone in men as a direct result of aging. Supplementation with vitamins and minerals such as vitamin D and calcium have shown to slow down this demineralization process significantly. The primary mineral component of bone is known as Hydroxyapatite and a lesser-known effective bone supplement to help slow down bone demineralization is Microcrystalline Hydroxyapatite Concentrate (MHAC), a form of hydroxyapatite derived from cattle bone tissue.
What Bone Builder offers
Bone Builder from Metagenics offers a blend of Calcium and Phosphorous in addition to 1.5 grams of MHAC in a readily absorbed form to help ensure optimal bone health in aging individuals and people at higher risk for fracture-related injuries. It is important to note the importance of Vitamin D supplementation in bone health upkeep and we recommend taking additional vitamin D to help further improve your bone health.
Why Bone Builder
Supplementation with MHAC in previous research has shown MHAC to be effective in increasing bone density levels in post menopausal women. Metagenics Bone Builder is one of very few bone supplements on the market containing MHAC, providing both Calcium and Hydroxyapatite to prevent bone demineralization and slow down progression of bone density loss. Previous research has also shown MHAC to reduce bone turnover and fracture risk for post menopausal women, two strong indicators for bone health.
If interested in supplements containing higher amounts of MHAC, other Bone Builder products are available for more severe cases of bone density loss.
Dosage and precautions for Bone Builder
Directions: Take three tablets once daily or as directed by your healthcare practitioner.
Caution: If pregnant, nursing or taking antibiotics or cardiovascular medication, consult your healthcare practitioner before use. Keep out of reach of children.
Bone Builder ingredients
Ingredient | Amount Per Serving | % Daily Value |
---|---|---|
Total Carbohydrate | <1 g | <1%* |
Dietary Fiber | <1 g | 2%* |
Calcium (as MCHC and dicalcium phosphate) | 620 mg | 48% |
Phosphorus (as MCHC and dicalcium phosphate) | 360 mg | 29% |
Microcrystalline Hydroxyapatite Concentrate (MCHC) | 1.5 g | * |
This product is non-GMO and gluten-free.
Serving Size: 3 Tablets
Servings Per Container: 90. Other serving size might also be availane.
Other Ingredients: Microcrystalline cellulose, stearic acid (vegetable), cellulose, croscarmellose sodium, silica, and coating (hypromellose, medium-chain triglycerides, and hydroxypropylcellulose).
*Percent Daily Values are based on a 2,000 calorie diet.
References for Bone Builder
"Cao, J. J., Gregoire, B. R., Gao, H., & Horst, R. L. (2014). Effects of microcrystalline hydroxyapatite on bone health in postmenopausal women: A randomized controlled trial. Clinical Interventions in Aging, 9, 2087–2095. https://doi.org/10.2147/CIA.S68825
"Shen, C. L., Yeh, J. K., , C., Cao, J. J., Stoecker, B. J., & Dagda, R. Y. (2010). Green tea polyphenols mitigate deterioration of bone microarchitecture in middle-aged female rats. Osteoporosis International, 21(10), 1723–1734. https://doi.org/10.1007/s00198-009-1160-3
"Depciuch, J., Kaczmarczyk-Sedlak, I., Sedlak, L., & Nowak, B. (2018). Microcrystalline hydroxyapatite—a review of properties and clinical applications. Nutrients, 10(10), 1348. Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients
"Uenishi, K., Ishida, H., Toba, Y., Aoe, S., Itabashi, A., & Takada, Y. (2018). Effect of microcrystalline hydroxyapatite on bone mineral density and bone strength in pre- and postmenopausal women: A randomized placebo-controlled trial. Biological Trace Element Research, 181(2), 292–298. https://doi.org/10.1007/s12011-017-1182-7
"Cangussu, L. M., Nahás-Neto, J., Orsatti, C. L., Bueloni-Dias, F. N., Nahas, E. A., & Nahas, Neto, J. (2015). Effect of calcium hydroxyapatite (microcrystalline hydroxyapatite) on bone metabolism and bone mass in postmenopausal women: A randomized placebo-controlled trial. Clinical Cases in Mineral and Bone Metabolism, 12(3), 222–226. Osteoporosi: quali sono le cause? E quali sono le possibili cure? - CCMBM
"Rondanelli, M., Perna, S., Rezzani, C., Orsini, F., & Infantino, V. (2020). Microcrystalline hydroxyapatite in bone health: A review on the supplementation perspectives and clinical outcomes. Nutrients, 12(12), 3629. Ultra-Marathon-Induced Increase in Serum Levels of Vitamin D Metabolites: A Double-Blind Randomized Controlled Trial